A fundamental underpinning of the silicones industry’s commitment to product stewardship is the belief that comprehensive, robust, risk-based assessments utilizing a WoE approach should be the primary driver for development of chemical regulatory policy. A core requirement for the development of scientific assessments is the availability of high-quality data. The silicones industry’s willingness to develop those data is an illustration of the industry’s commitment to the generation of sound science to support chemical regulatory decision-making.